Enhanced plug & play adaptive optics device, called MicAO, is now compatible with a larger range of objective lenses and larger field of view cameras, such as sCMOS.
By correcting the system and sample-induced aberrations, MicAO allows users to significantly improve the image contrast in spinning disk microscopy and to increase the 3D localization precision in single molecule detection methods using aberration-free astigmatism (3D PALM/STORM). This ability to correct aberrations allows the user to image cellular structures deeper in biological samples, up to a depth of 50µm.
Highlights:
- compatible with larger range of objective lenses
- accommodates larger field-of-view cameras, such as sCMOS
- user can improve image contrast in spinning disk microscopy
- corrects aberrations
