Chemical Processor for Cryogenic Chemistry

April 6, 2020

The CryoFlowSkid enables 3 step syntheses for the continuous production of chemical intermediates or active pharmaceutical ingredients in kg quantities per hour.


In particular, syntheses with highly exothermic reaction steps and proceeding through unstable intermediates can be carried out in the CryoFlowSkid with significantly higher efficiency than with a batch process. Thus the technology for e.g. organometallic chemistry can often be considerably intensified.


The compact, mobile system can be operated in a typical chemical pilot plant environment and it is fully automated. The system is highly modular so that e.g. the reactors can be easily exchanged.


The CryoFlowSkid was developed by De Dietrich Process Systems GmbH (D, Mainz) together with InnoSyn B.V. (NL, Geleen). InnoSyn contributes to the chemical process know-how and the flow reactors. These core components developed by InnoSyn are manufactured from different metals in a 3D printing process. De Dietrich Process Systems, as the manufacturer of the entire system, is responsible for the engineering, production and worldwide sales and service of the complete CryoFlowSkid. For this joint co-operation, the two companies signed a collaboration contract.